Planning Doesn't Work

Parenting after infertility, dogs, goats, my life

November 4, 2011 November 4, 2011

Filed under: Uncategorized — MSW @ 10:06 pm

Not surprisingly I can’t stop thinking about my elevated betas. I’ve done some reading and found a research article on IVF & monozygotic multiples. This is what it said:

It can be summarized from the literature that prolonged culture as well as manipulations of the zona pellucida (ICSI and/or assisted hatching) could lead to an increased rate of monozygotic multiples. To minimize the resulting risks such as increased abortion rates, increased perinatal morbidity and mortality (Al‐Nuaim and Jenkins, 2002), assisted hatching in combination with ICSI and blastocyst culture should be critically performed. The aim of therapy should be the transfer of only one blastocyst in as many patients as possible. In our opinion the incidence of 5.9–8.9% monozygotic multiples after ICSI and blastocyst transfer reported in the literature requires the prior informing of patients of the uncertainties until this phenomenon and its risk factors are better understood.

We did ICSI and blastocyst culture.  I know that the clinic did assisted hatching on the embryo from our failed transfer in the summer. I don’t know know if they did for this recent one. But 5.9-8.9% is a high enough chance to be significant in my mind.

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2 Responses to “November 4, 2011”

  1. Yeah, that is statistically significant, to be euphemistic about it. I’ve been thinking of you lots today, wondering about this very thing. Hope you are handling the wondering ok.

  2. slowmamma Says:

    I’m glad you just have a few more days of wondering. I guess I may be the wrong person to offer support since I am walking evidence that twin pregnancies are risky but I did a lot of reading during my pregnancy and I remember that the highest risk for complications in twin pregnancies was 6% for monozygotic boys. Increased risk is stressful but even that gives you a 94% chance of a good outcome.


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