Not surprisingly I can’t stop thinking about my elevated betas. I’ve done some reading and found a research article on IVF & monozygotic multiples. This is what it said:
It can be summarized from the literature that prolonged culture as well as manipulations of the zona pellucida (ICSI and/or assisted hatching) could lead to an increased rate of monozygotic multiples. To minimize the resulting risks such as increased abortion rates, increased perinatal morbidity and mortality (Al‐Nuaim and Jenkins, 2002), assisted hatching in combination with ICSI and blastocyst culture should be critically performed. The aim of therapy should be the transfer of only one blastocyst in as many patients as possible. In our opinion the incidence of 5.9–8.9% monozygotic multiples after ICSI and blastocyst transfer reported in the literature requires the prior informing of patients of the uncertainties until this phenomenon and its risk factors are better understood.
We did ICSI and blastocyst culture. I know that the clinic did assisted hatching on the embryo from our failed transfer in the summer. I don’t know know if they did for this recent one. But 5.9-8.9% is a high enough chance to be significant in my mind.